NEBIVOLOL

Product Description

Dayaram pharma chem is world’s top leading manufacturer,exporter, trader and supplier of NebivololAPI as well as finished pharmaceutical products of Nebivolol among thepharmaceutical companies. Our product Nebivolol is widely used and appreciatedby our group companies and also our customers and users all around the nations.We offer the Nebivololin very affordable price.

Dayaram pharma chem and Dayaramgroup companies are the very well-known manufacturer, supplier anddistributor of Nebivolol products.

Dayaram pharma chem are manufacturing and exporting verylarge quantity of Nebivolol incountries like Hungary, El Salvador, Paraguay, Germany, Argentina, Austria,Romania, Pakistan, Portugal, Latvia, Philippines, Honduras, Switzerland,France, Chile, Estonia, North Macedonia, Lithuania, Guatemala, Croatia, Kenya, Ireland, Serbia, Belgium, Bulgaria, Bosnia & Herzegovina, Netherlands,Colombia, Dominican Republic, Bangladesh, Vietnam, Venezuela, Mexico, Brazil,Iraq, Bolivia, Ecuador, United Arab Emirates, Sri Lanka, Czechia, Australia,Jordan, Spain, Singapore, United Kingdom, Egypt, Slovakia, Greece, Peru,Nigeria, United States, Turkey, Malaysia, Poland, Algeria, Morocco, Hong Kong,Saudi Arabia, South Korea, Denmark, Taiwan, Finland, Thailand, Canada,Indonesia, Italy, Russia and many other countries.

Nebivolol comes inthe beta blocker category of medicine. Usually Nebivolol used to treat the highblood pressure.

Nebivolol decrease theblood pressure by slowing the heart rate and by relaxing the muscles and bloodvessels by this Nebivolol improve the blood flow. Usually Nebivolol is not thefirst choice medication but it is given when necessary.

SYNONYMS OFNEBIVOLOL: Narbivolol, Nebivolol, Nebivololum.

IUPAC NAME OF NEBIVOLOL: 1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-{[2-(6-fluoro-3, 4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]amino} ethan-1-ol

CAS NO: 118457-14-0

FORMULA: C22H25F2NO4

MOLECULARMASS:405.43 g/mol

STORAGE CONDITION: Store in room temperature in dry place, awayfrom light and moisture. Do not put in fridge, kitchen or bathroom. Keep awayfrom children and pets.

HOW TO USE: Take this medication one time per day orallywith or without food. Take medication regularly to get more benefits of it, donot forget to take medication, take medication as soon you remember.

HOWNEBIVOLOL WORKS: Nebivolol is normally beta-1 adrenergic receptor antagonist whichincreases the blood flow and cardiac output by relaxing the blood vessels inthe body. The effect of Nebivolol normally stays for 48 hrs.

PHARMACOKINETICS OF NEBIVOLOL: Normally Nebivolol absorbed orally and bind withthe 98% of albumin. Nebivolol inhibits the btea-1-adrenargic receptor by thisthe blood flow increases in heart and body. The half-life of Nebivolol isgenerally 12hrs. Nebivolol normally excreted 38% by urination and 44% by faces.

SIDE EFFECTS OF NEBIVOLOL: The normal side effects like dizziness,headache, weakness, sloe heartbeat, nausea, insomnia are often seen in thepatients. Nebivolol sometime cause reduces the blood flow to the feet so feetcold happens some time. If you see some serious side effects like bluefigures/toes, fainting, slow heartbeats, mental/ mood swings.

PRECAUTIONS WHILE TAKINGNEBIVOLOL: Before takingthe Nebivolol tell your doctor if you are allergic to it. Tell your doctor ifyou have any problem like heart problem, blood circulation problem, breathingproblem, liver/kidney problem. Kindly avoid taking medicines if you are inpregnancy period. Before taking the medication tell your doctor if you takingthe other medication or having past disease. If the side effects seen worsenkindly contact to your doctor.

CDSCO APPROVAL: Nebivolol + Hydrochlorthiazide approved byCDSCO in Indian in 23.12.2004, Indapamide (SR) 1.5mg/1.5mg + Nebivolol2.5mg/5mg tabletapproved by CDSCO in Indian in 12.05.2010,

Amlodipine (5mg) + Nebivolol (5mg) tablet (addl. Strength)approvedby CDSCO in Indian in 06.09.2007,

Nebivolol 5mg + S(-) Amlodipine 2.5mg Tabletapproved by CDSCO inIndian in 14.09.2004,

Nebivolol (as HCl) 5mg + Valsartan 80mg Capsule approved by CDSCOin Indian in 25.01.2006,

Nebivolol tabs & bulk import approved by CDSCO in Indian in 12.07.2002.

FORMULATIONS AVAILABLE IN MARKET:

Nebivolol 5mg tablets

Nebivolol 10mg tablets

Nebivolol 2.5mg tablets

Nebivolol 5mg + Amlodipine 5mg tablets

Nebivolol 5mg + Cilnidipine 10mg tablets

Nebivolol 5mg +Valsartan 80mgtablets

Nebivolol 5mg + Telmisartan 40 mgtablets

Note: Product protected by valid patents are not offered for sale incountries where such patents are still valid and its liability is at BuyersRisk.

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com