ADAPALENE

Product Description

Adapalene finished formulations moreover Adapalene API. DayaramPharma Chem is the huge manufacturer, exporter and supplier of Adapalene API andformulation situated in Ankleshwar, Gujarat, India.

Dayaram Pharma Chem provides API and finishedformulations of Adapalene in allover Indian states Like Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab,Delhi, Bihar, Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh, Uttar Pradesh,Rajasthan, Karnataka, Jammu Kashmir Etc.

Dayaram Pharma Chem is also large exporter of the APIand finished pharmaceutical products of Adapalenein many countries for years. The countries where we exporting are Nepal, SriLanka, Malaysia, Philippines, Kenya, Singapore, Hong Kong, Pakistan, UnitedArab Emirates, United States, Puerto Rico, Argentina, Egypt, Qatar, Taiwan,Algeria, Jordan, Uruguay, United Kingdom, Canada, Bangladesh, New Zealand,Saudi Arabia, Australia, Colombia, France, Vietnam, Ireland, Iraq, Thailand,South Africa, Ecuador, Serbia, Peru, Indonesia, Morocco, Israel, Greece, Romania,Mexico, Iran, Switzerland, Norway, Italy, Denmark, Belgium, South Korea,Netherlands, Venezuela, Hungary, Chile, Sweden, Germany, Ukraine, Spain,Poland, Brazil, Turkey, Russia, Japan and many more countries.

Adapalene is onekind of skin care product. Adapalene belongs to the retinoid like compound.Adapalene used in skin care and works by stopping the pimples from formingunder the skin.

SYNONYMS: Adapalene, Adapalnem, Adapaleno, Adapalenum

IUPAC NAME: 6-[3-(adamantan-1-yl)-4-methoxyphenyl] naphthalene-2-carboxylicacid

CAS NO: 106685-40-9 

FORMULA: C₂₈H₂₈O₃

MOLECULAR MASS: 412.52 g/mol

STORAGE CONDITIONS: Store in cool and dry place, away fromdirect heat and light.

Do not place in bathroom or kitchen. Keep away from the childrenand pet.

HOW TO USE: Use this medication on your skin. Wash cleanand dry your skin before using the medication. Wash your hands before using thegel, tube or lotion. Do not apply medicine on eyes.

HOW ADAPALENE WORKS: Adapalene works by inhibiting the acne formulation underthe skin. Adapalene binds with the retinoid receptor and activates it.Adapalene also use in the beauty care products.

PHARMACOKINETICS: Adapaleneabsorbed through skin after topical application, used only 2g of 0.3% gel. The half-lifeof Adapalene 0.3% gel id between 7-51 hours. Almost 25% of drug metabolised inthe body. 75% of drug remains unchanged and eliminated by the biliary route.

SIDE EFFECTS: The stinginglike sensation occurs after applying the medicine. Side effects like burning,irritation, swelling of skin, itching, dryness of skin, burning are seen in thefirst 5-6 days of using the medicine. If you see side effects like irritation,intense burning, redness of eye, skin discolouration contact your doctor.

PRECAUTIONS: Before usingthe medication tell your doctor if you are allergic to Adapalene. Tell yourdoctor if you have any problem like skin problem, eczema etc. Do not apply thismedicine on open wounds. Do not apply on eye or burned part of skin.

CDSCO APPROVAL: Adapalene 0.1% w/w approved by CDSCO inIndia in 15.03.2001,

Adapalene 0.1% + Benzoyl Peroxide 2.5% gel approved by CDSCO inIndia in 31.10.2008,

Adapalene + clindamycin gel approved by CDSCO in India in01.05.2003

FORMULATION AVAILABLE IN MARKET:

Adapalene 0.1% w/w cream

Adapalene 0.1% + Benzoyl Peroxide 2.5% gel

Adapalene + clindamycin gel

Adapalene 0.1% w/w + clindamycin gel 0.1%w/w cream

Adapalene 1%w/w cream

Adapalene 0.1% w/w cream

Adapalene 0.10% w/v gel

Adapalene 0.1% w/w + benzoyl peroxide 2.5%w/w cream

Adapalene 0.02 %w/w + Azithromycin 2 %w/w cream

Adapalene 0.1 %w/v +Allantoin 1 %w/w + Clindamycin 1 %w/w gel

Note: Product protected by valid patents are notoffered for sale in countries where such patents are still valid and itsliability is at Buyers Risk